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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC24A
All Species:
30.91
Human Site:
S1040
Identified Species:
52.31
UniProt:
O95486
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95486
NP_068817.1
1093
119749
S1040
A
R
I
I
A
F
I
S
W
L
R
E
Q
R
P
Chimpanzee
Pan troglodytes
XP_527165
1093
119711
S1040
A
R
I
I
A
F
I
S
W
L
R
E
Q
R
P
Rhesus Macaque
Macaca mulatta
XP_001109620
1093
119674
S1040
A
R
I
I
A
F
I
S
W
L
R
E
Q
R
P
Dog
Lupus familis
XP_850736
1100
120445
S1047
A
R
I
I
A
F
I
S
W
L
R
E
Q
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3U2P1
1090
118764
S1037
A
R
I
A
A
F
I
S
W
L
R
E
Q
R
P
Rat
Rattus norvegicus
NP_001099250
1089
118849
S1036
A
R
M
T
A
F
I
S
W
L
R
E
Q
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510651
1234
134485
S1181
A
R
T
R
A
F
I
S
W
L
R
E
H
R
P
Chicken
Gallus gallus
XP_414630
1100
120006
S1047
I
R
T
V
A
F
I
S
W
L
R
E
Q
R
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001340708
1097
118527
D1044
C
R
M
R
A
F
V
D
W
L
R
E
R
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_394884
843
95632
E795
N
F
V
F
S
L
Q
E
E
K
P
Y
P
A
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784354
1353
146633
R1285
L
M
C
P
P
N
M
R
L
L
P
L
Y
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SFU0
1038
113942
Y990
L
R
E
S
D
P
S
Y
H
P
M
C
F
L
V
Baker's Yeast
Sacchar. cerevisiae
P40482
926
103617
S878
L
Y
I
V
R
G
A
S
L
S
E
P
V
N
H
Red Bread Mold
Neurospora crassa
Q7S4P3
950
103512
I902
K
S
K
G
V
G
S
I
T
L
P
H
L
Y
I
Conservation
Percent
Protein Identity:
100
99.4
97.7
92.1
N.A.
88.3
88.2
N.A.
69.1
74
N.A.
59.5
N.A.
N.A.
44.7
N.A.
28.7
Protein Similarity:
100
99.8
98.2
94.2
N.A.
92.4
92
N.A.
76.2
83
N.A.
71.4
N.A.
N.A.
59.4
N.A.
43
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
80
80
N.A.
60
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
80
86.6
N.A.
80
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.5
29.7
31.7
Protein Similarity:
N.A.
N.A.
N.A.
53.5
48.2
49.7
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
8
65
0
8
0
0
0
0
0
0
8
0
% A
% Cys:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
8
8
0
8
65
0
0
0
% E
% Phe:
0
8
0
8
0
65
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
15
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
8
8
0
8
% H
% Ile:
8
0
43
29
0
0
58
8
0
0
0
0
0
0
8
% I
% Lys:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
22
0
0
0
0
8
0
0
15
79
0
8
8
8
8
% L
% Met:
0
8
15
0
0
0
8
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
8
8
8
0
0
0
8
22
8
8
0
65
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
0
50
0
0
% Q
% Arg:
0
72
0
15
8
0
0
8
0
0
65
0
8
65
0
% R
% Ser:
0
8
0
8
8
0
15
65
0
8
0
0
0
0
8
% S
% Thr:
0
0
15
8
0
0
0
0
8
0
0
0
0
8
0
% T
% Val:
0
0
8
15
8
0
8
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
8
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _